Dr Christopher Rose
900 Saint-Denis Street
Montreal, Quebec
Canada, H2X 0A9
Biographical Sketch
Dr. Christopher Rose is currently Professor in the Department of Medicine at the Université de Montréal. He is director of the Hepato-neuro laboratory which is located au Centre de Recherche du Centre Hospitalier de l’Université de Montréal (CRCHUM). Dr. Rose received his PhD (Neuroscience/Biomedical Sciences) from Université de Montréal in 2000. He continued his research interests in Europe by pursuing post-doctoral studies in Germany (Prof. Kettenmann, Berlin), Spain (Prof. Felipo, Valencia and Prof. Cordoba, Barcelona) and Norway (Dr. Ytrebo, Tromso). In doing so, he was the recipient of 3 prestigious post-doctoral fellowship awards from the Alexander von Humboldt Foundation (Germany), Canadian Institute of Health Research (Canada) and the European Association for the Study of the Liver (Europe).
Selected Scientific Contributions
Non-alcoholic fatty liver disease (NAFLD) is global public health problem and is currently the most common cause of chronic liver disease worldwide, affecting between 20-35% of the adult population. Its progression to non-alcoholic steatohepatitis (NASH) leads to end-stage liver disease (cirrhosis). Hepatic encephalopathy is a major neuropsychiatric complication of liver disease affecting close to 80% of patients with cirrhosis which negatively impacts on their quality of life as well as morbidity and mortality both pre- and post-liver transplant.
Research Interests
Dr. Rose’s research interests lie within the area of hepatic encephalopathy, a field in which he has been researching for over 25 years. Translational research is the primary objective of Dr. Rose’s laboratory and, therefore, his research program is based on a bench-to-bedside concept. Dr. Rose has a vested interest in identifying the pathogenic factors and the pathophysiological pathways involved in the development of cerebral complications associated with liver disease which ultimately will lead to novel therapeutic approaches, improving the management of patients with liver disease.